Hormonal Imbalances in America

Today I’ve provided a brief point paper on hormonal imbalances resulting from the American diet and how Growth Factor can help remedy these imbalances.         

Hormone imbalances

Currently there are more Americans facing hormonal imbalances and impaired hormone production than ever before. Hormonal imbalance is a disease – which means a disruption in the body’s normal function; therefore it needs to be remedied. When hormone production is impaired, physical and mental signs of imbalance become apparent.  These include weight gain, muscle atrophy, lingering soreness, poor physical performance, a decreased libido and mood imbalances. (1,2,3,4)

Diet, lifestyle and our hormones

Recent studies have identified the American diet, which is full of processed sugars, starches, meats, corn and soy as a major contributor to the dysfunction of chief regulating hormones. (5,6) The same is true with plastics which continuously emit estrogens and petrochemicals into our foods, further disrupting our natural hormone balance. (7,8)

Training and our hormones

Correct exercise promotes positive changes in the body when a correct diet is employed. However, there are circumstances where overtraining can occur, especially with athletes. Overtraining takes place when fatigue builds due to heavy training and full recovery is not allowed. Most athletes train against and often beyond this threshold. This can lead to muscle breakdown, suppressed anabolic hormone levels and increased catabolic hormone levels. This disruption is virtually identical to the dysfunction of hormone production in an unhealthy aging person. (9) 

The Solution

GF is an all-natural remedy for unhealthy aging at the cellular level. Our formula is a sustainable raw material that consists of a naturally derived growth matrix including IGF-1. Growth factors have the profound ability to balance hormones for men and women, raise male sex hormones, decrease insulin sensitivity, and produce increases in the function of mitochondria and nucleic acids (IE: DNA/RNA cellular rejuvenation). (10,11,12,13 )    


1.         Clemmons DR. Role of IGF-I in skeletal muscle mass maintenance. Trends Endocrinol Metabol 20, 7:349-356, 2009.

2.         Duan C, Ren H, Gao S. Insulin-like growth factors, IGF receptors and IGF-binding proteins: Roles in skeletal muscle growth and differentiation. Gen Comp Endocr 167, 344-351, 2010.

3.         Smith JT. Insulin-like growth factor-I regulation of immune function: A potential therapeutic target in autoimmune diseases. Pharmacol Rev 62, 2:199-236, 2010.

4.         Yen SSC, Laughlin GA. Aging and the adrenal cortex. Exp Gerontol 33, 7/8:897-910, 1998.

5.         Behr M, Oehlmann J, Wagner M. Estrogens in the daily diet: In vitro analysis indicates that estrogenic activity is omnipresent in foodstuff and infant formula. Food Chem Toxicol 49, 2681-2688. 2011.

6.         de Vendomois JS, Roullier F, Cellier D, et al. A comparison of the effects of three GM corn varieties on mammalian health. Int J Biol Sci 5, 7:706-726. 2009.

7.         Muncke J. Exposure to endocrine disrupting compounds via the food chain: Is packaging a relevant source? Sci Total Environ 407, 4549-4559, 2009.

8.         Wagner M, Oehlmann J. Endocrine disruptors in bottled mineral water: Estrogenic activity in the E-Screen. J Steroid Biochem Mol Biol 127, 128-135, 2011.

9.         Fry RW, Morton AR, Keast D. Overtraining in athletes. An update. Sports Med 12, 1:32-35. 1991.

10.       Hussain MA, Schmitz O, Mengel A, et al. Insulin-like growth factor I stimulates lipid oxidation, reduces protein oxidation, and enhances insulin sensitivity in humans. J Clin Invest 92, 2249- 2256, 1993.

11.       l’Allemand D, Penhoat A, Lebrethon MC, et al. Insulin-like growth factors enhance steroidogenic enzyme and corticotropin receptor messenger ribonucleic acid levels and corticotropin steroidogenic responsiveness in cultured human adrenocortical cells. J Clin Endocrinol Metab 81, 11:3892-3897. 1996.

12.       Pham-Huu-Trung MT, Villette JM, Boygo A, et al. Effects of insulin-like growth factor I (IGF-I) on enzymatic activity in human adrenocortical cells. Interactions with ACTH. J Steroid Biochem Mol Bio 39, 6:903-909. 1991.

13.           Mattson MP, Zhang Y, Bose S. Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis, and cell injury, but not ATP depletion in hippocampal neurons deprived glucose. Exp Neurol 121, 1:1-13. 1993.

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